Choledocholithiases in a child with Hemoglobin Evans [alpha2 62(E11) Val→Met]
نویسندگان
چکیده
We present the first description of choledocholithiases in a 10-year-old boy with Hemoglobin Evans. Although biliary stones are much less common in children than in adults, epigastric pain in children with known hemolytic status should alert the physician to the possibility of biliary colic.
منابع مشابه
A novel silent posttranslational mechanism converts methionine to aspartate in hemoglobin Bristol (beta 67[E11] Val-Met->Asp).
The first reported case of congenital Heinz body hemolytic anemia was subsequently shown to be caused by an unstable hemoglobin, Hb Bristol [beta 67(E11) Val-Asp]. This has become one of the classic models of an unstable hemoglobin, the hydrophilic aspartate disrupting the hydrophobic heme pocket. We have restudied this original case, who remains clinically well after nearly 50 years of severe ...
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عنوان ژورنال:
دوره 4 شماره
صفحات -
تاریخ انتشار 2016